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Leptin-Induced Angiogenesis of EA.Hy926 Endothelial Cells via the Akt and Wnt Signaling Pathways In Vitro and In Vivo

Angiogenesis involves the activation of endothelial cells followed by capillary formation. Leptin, the protein product of the ob gene, can induce the angiogenic potential of endothelial cells. However, the underlying cellular mechanism still remains to be elicited. We firstly evaluated the in vitro...

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Detalles Bibliográficos
Autores principales: Yu, Fei, Fu, Runqing, Liu, Lu, Wang, Xiaoting, Wu, Tingting, Shen, Wei, Gui, Zhipeng, Mo, Xiumei, Fang, Bing, Xia, Lunguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836761/
https://www.ncbi.nlm.nih.gov/pubmed/31736756
http://dx.doi.org/10.3389/fphar.2019.01275