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Stabilization of cyclohexanone monooxygenase by computational and experimental library design

Enzymes often by far exceed the activity, selectivity, and sustainability achieved with chemical catalysts. One of the main reasons for the lack of biocatalysis in the chemical industry is the poor stability exhibited by many enzymes when exposed to process conditions. This dilemma is exemplified in...

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Detalles Bibliográficos
Autores principales: Fürst, Maximilian J. L. J., Boonstra, Marjon, Bandstra, Selle, Fraaije, Marco W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836875/
https://www.ncbi.nlm.nih.gov/pubmed/31124128
http://dx.doi.org/10.1002/bit.27022