Tissue-type plasminogen activator selectively inhibits multiple toll-like receptors in CSF-1-differentiated macrophages

Tissue-type plasminogen activator (tPA) is a major activator of fibrinolysis, which also attenuates the pro-inflammatory activity of lipopolysaccharide (LPS) in bone marrow-derived macrophages (BMDMs) and in vivo in mice. The activity of tPA as an LPS response modifier is independent of its proteina...

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Detalles Bibliográficos
Autores principales: Das, Lipsa, Azmoon, Pardis, Banki, Michael A., Mantuano, Elisabetta, Gonias, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837328/
https://www.ncbi.nlm.nih.gov/pubmed/31697716
http://dx.doi.org/10.1371/journal.pone.0224738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837328/
https://www.ncbi.nlm.nih.gov/pubmed/31697716
http://dx.doi.org/10.1371/journal.pone.0224738

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