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Phase variation of a signal transduction system controls Clostridioides difficile colony morphology, motility, and virulence
Recent work has revealed that Clostridioides difficile, a major cause of nosocomial diarrheal disease, exhibits phenotypic heterogeneity within a clonal population as a result of phase variation. Many C. difficile strains representing multiple ribotypes develop two colony morphotypes, termed rough a...
Autores principales: | Garrett, Elizabeth M., Sekulovic, Ognjen, Wetzel, Daniela, Jones, Joshua B., Edwards, Adrianne N., Vargas-Cuebas, Germán, McBride, Shonna M., Tamayo, Rita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837544/ https://www.ncbi.nlm.nih.gov/pubmed/31658249 http://dx.doi.org/10.1371/journal.pbio.3000379 |
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