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SorCS1-mediated sorting in dendrites maintains neurexin axonal surface polarization required for synaptic function

The pre- and postsynaptic membranes comprising the synaptic junction differ in protein composition. The membrane trafficking mechanisms by which neurons control surface polarization of synaptic receptors remain poorly understood. The sorting receptor Sortilin-related CNS expressed 1 (SorCS1) is a cr...

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Detalles Bibliográficos
Autores principales: Ribeiro, Luís F., Verpoort, Ben, Nys, Julie, Vennekens, Kristel M., Wierda, Keimpe D., de Wit, Joris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837583/
https://www.ncbi.nlm.nih.gov/pubmed/31658245
http://dx.doi.org/10.1371/journal.pbio.3000466