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Epigenetic switching as a strategy for quick adaptation while attenuating biochemical noise

Epigenetic switches are bistable, molecular systems built from self-reinforcing feedback loops that can spontaneously switch between heritable phenotypes in the absence of DNA mutation. It has been hypothesized that epigenetic switches first evolved as a mechanism of bet-hedging and adaptation, but...

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Detalles Bibliográficos
Autores principales: Gómez-Schiavon, Mariana, Buchler, Nicolas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837633/
https://www.ncbi.nlm.nih.gov/pubmed/31658246
http://dx.doi.org/10.1371/journal.pcbi.1007364