Structural characterization of the saxitoxin-targeting APTSTX1 aptamer using optical tweezers and molecular dynamics simulations

Optical tweezers have enabled the exploration of picoNewton forces and dynamics in single–molecule systems such as DNA and molecular motors. In this work, we used optical tweezers to study the folding/unfolding dynamics of the APTSTX1–aptamer, a single-stranded DNA molecule with high affinity for sa...

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Detalles Bibliográficos
Autores principales: Casanova-Morales, Nathalie, Figueroa, Nataniel L., Alfaro, Karol, Montenegro, Felipe, Barrera, Nelson P., Maze, J. R., Wilson, Christian A. M., Conejeros, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837747/
https://www.ncbi.nlm.nih.gov/pubmed/31697710
http://dx.doi.org/10.1371/journal.pone.0222468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837747/
https://www.ncbi.nlm.nih.gov/pubmed/31697710
http://dx.doi.org/10.1371/journal.pone.0222468

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