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Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types in the metabolic response to IL10 remain to be defined. We demonstrate here that selective...

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Detalles Bibliográficos
Autores principales: Rajbhandari, Prashant, Arneson, Douglas, Hart, Sydney K, Ahn, In Sook, Diamante, Graciel, Santos, Luis C, Zaghari, Nima, Feng, An-Chieh, Thomas, Brandon J, Vergnes, Laurent, Lee, Stephen D, Rajbhandari, Abha K, Reue, Karen, Smale, Stephen T, Yang, Xia, Tontonoz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837845/
https://www.ncbi.nlm.nih.gov/pubmed/31644425
http://dx.doi.org/10.7554/eLife.49501