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The Liver-Stage Plasmodium Infection Is a Critical Checkpoint for Development of Experimental Cerebral Malaria

Cerebral malaria is a life-threatening complication of malaria in humans, and the underlying pathogenic mechanisms are widely analyzed in a murine model of experimental cerebral malaria (ECM). Here, we show abrogation of ECM by hemocoel sporozoite-induced infection of a transgenic Plasmodium berghei...

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Detalles Bibliográficos
Autores principales: Sato, Yuko, Ries, Stefanie, Stenzel, Werner, Fillatreau, Simon, Matuschewski, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837997/
https://www.ncbi.nlm.nih.gov/pubmed/31736970
http://dx.doi.org/10.3389/fimmu.2019.02554