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Carbamazepine Alleviates Retinal and Optic Nerve Neural Degeneration in Diabetic Mice via Nerve Growth Factor-Induced PI3K/Akt/mTOR Activation

Aim: Diabetic retinopathy causes loss of vision in adults at working-age. Few therapeutic options are available for treatment of diabetic retinopathy. Carbamazepine (CARB), a widely used antiepileptic drug, was recently accounted for its neuroprotective effect. Nerve growth factor (NGF) activates va...

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Detalles Bibliográficos
Autores principales: Elsherbiny, Nehal M., Abdel-Mottaleb, Yousra, Elkazaz, Amany Y., Atef, Hoda, Lashine, Rehab M., Youssef, Amal M., Ezzat, Wessam, El-Ghaiesh, Sabah H., Elshaer, Rabie E., El-Shafey, Mohamed, Zaitone, Sawsan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838003/
https://www.ncbi.nlm.nih.gov/pubmed/31736682
http://dx.doi.org/10.3389/fnins.2019.01089