Identification of HLA-A*02:06:01 as the primary disease susceptibility HLA allele in cold medicine-related Stevens-Johnson syndrome with severe ocular complications by high-resolution NGS-based HLA typing

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening acute inflammatory vesiculobullous reactions of the skin and mucous membranes. These severe cutaneous drug reactions are known to be caused by inciting drugs and infectious agents. Previously, we have reported t...

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Detalles Bibliográficos
Autores principales: Nakatani, Ken, Ueta, Mayumi, Khor, Seik-Soon, Hitomi, Yuki, Okudaira, Yuko, Masuya, Anri, Wada, Yuki, Sotozono, Chie, Kinoshita, Shigeru, Inoko, Hidetoshi, Tokunaga, Katsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838058/
https://www.ncbi.nlm.nih.gov/pubmed/31700100
http://dx.doi.org/10.1038/s41598-019-52619-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838058/
https://www.ncbi.nlm.nih.gov/pubmed/31700100
http://dx.doi.org/10.1038/s41598-019-52619-2

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