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Differential interaction between DARC and SDF-1 on erythrocytes and their precursors

The Duffy Antigen Receptor for Chemokines (DARC) is expressed on erythrocytes and on endothelium of postcapillary venules and splenic sinusoids. Absence of DARC on erythrocytes, but not on endothelium, is referred to as the Duffy negative phenotype and is associated with neutropenia. Here we provide...

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Detalles Bibliográficos
Autores principales: Klei, T. R. L., Aglialoro, F., Mul, F. P. J., Tol, S., Ligthart, P. C., Seignette, I. M., Geissler, J., van den Akker, E., van Bruggen, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838059/
https://www.ncbi.nlm.nih.gov/pubmed/31700087
http://dx.doi.org/10.1038/s41598-019-52186-6