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Double deficiency of toll-like receptors 2 and 4 alters long-term neurological sequelae in mice cured of pneumococcal meningitis

Toll-like receptor (TLR) 2 and 4 signalling pathways are central to the body’s defence against invading pathogens during pneumococcal meningitis. Whereas several studies support their importance in innate immunity, thereby preventing host mortality, any role in protecting neurological function durin...

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Detalles Bibliográficos
Autores principales: Too, Lay Khoon, Yau, Belinda, Baxter, Alan G., McGregor, Iain S., Hunt, Nicholas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838097/
https://www.ncbi.nlm.nih.gov/pubmed/31700009
http://dx.doi.org/10.1038/s41598-019-52212-7