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Double deficiency of toll-like receptors 2 and 4 alters long-term neurological sequelae in mice cured of pneumococcal meningitis
Toll-like receptor (TLR) 2 and 4 signalling pathways are central to the body’s defence against invading pathogens during pneumococcal meningitis. Whereas several studies support their importance in innate immunity, thereby preventing host mortality, any role in protecting neurological function durin...
Autores principales: | Too, Lay Khoon, Yau, Belinda, Baxter, Alan G., McGregor, Iain S., Hunt, Nicholas H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838097/ https://www.ncbi.nlm.nih.gov/pubmed/31700009 http://dx.doi.org/10.1038/s41598-019-52212-7 |
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