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Revealing Hi-C subcompartments by imputing inter-chromosomal chromatin interactions
Higher-order genome organization and its variation in different cellular conditions remain poorly understood. Recent high-coverage genome-wide chromatin interaction mapping using Hi-C has revealed spatial segregation of chromosomes in the human genome into distinct subcompartments. However, subcompa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838123/ https://www.ncbi.nlm.nih.gov/pubmed/31699985 http://dx.doi.org/10.1038/s41467-019-12954-4 |