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Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures

Heat shock protein 90 (Hsp90) is a widely investigated target for anticancer therapy. The experimental Hsp90 inhibitors ICPD47 and ICPD62 demonstrated anticancer activity against colorectal, osteosarcoma and cervical cancer cell lines. However, their anticancer activity has not been investigated aga...

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Detalles Bibliográficos
Autores principales: Daunys, Simonas, Matulis, Daumantas, Petrikaitė, Vilma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838130/
https://www.ncbi.nlm.nih.gov/pubmed/31700053
http://dx.doi.org/10.1038/s41598-019-52652-1