Genetic Ablation of Calcium-independent Phospholipase A(2)γ Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice

Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) in mice results in marked damage of mitochondria and enhanced autophagy in glomerular visceral epithelial cells (GECs) or podocytes. The present study addresses the role of iPLA(2)γ in glomerular injury. In adriamycin nephrosis,...

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Detalles Bibliográficos
Autores principales: Elimam, Hanan, Papillon, Joan, Guillemette, Julie, Navarro-Betancourt, José R., Cybulsky, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838178/
https://www.ncbi.nlm.nih.gov/pubmed/31700134
http://dx.doi.org/10.1038/s41598-019-52834-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838178/
https://www.ncbi.nlm.nih.gov/pubmed/31700134
http://dx.doi.org/10.1038/s41598-019-52834-x

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