Cargando…

Genetic Ablation of Calcium-independent Phospholipase A(2)γ Exacerbates Glomerular Injury in Adriamycin Nephrosis in Mice

Genetic ablation of calcium-independent phospholipase A(2)γ (iPLA(2)γ) in mice results in marked damage of mitochondria and enhanced autophagy in glomerular visceral epithelial cells (GECs) or podocytes. The present study addresses the role of iPLA(2)γ in glomerular injury. In adriamycin nephrosis,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Elimam, Hanan, Papillon, Joan, Guillemette, Julie, Navarro-Betancourt, José R., Cybulsky, Andrey V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838178/ https://www.ncbi.nlm.nih.gov/pubmed/31700134 http://dx.doi.org/10.1038/s41598-019-52834-x

Ejemplares similares

Role of IRE1α in podocyte proteostasis and mitochondrial health
por: Navarro-Betancourt, José R., et al.
Publicado: (2020)

Regulation of Ste20-like kinase, SLK, activity: Dimerization and activation segment phosphorylation
por: Cybulsky, Andrey V., et al.
Publicado: (2017)

Analysis of gene expression and use of connectivity mapping to identify drugs for treatment of human glomerulopathies
por: Chung, Chen-Fang, et al.
Publicado: (2023)

Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy
por: Kaufman, Daniel Robert, et al.
Publicado: (2017)

Nephrosis
Publicado: (1931)

Chronic Nephrosis
por: Matthew, Edwin, et al.
Publicado: (1933)

GLOMERULAR PERMEABILITY : ULTRASTRUCTURAL STUDIES IN EXPERIMENTAL NEPHROSIS USING HORSERADISH PEROXIDASE AS A TRACER
por: Venkatachalam, M. A., et al.
Publicado: (1969)

AN ULTRASTRUCTURAL STUDY OF GLOMERULAR PERMEABILITY IN AMINONUCLEOSIDE NEPHROSIS USING CATALASE AS A TRACER PROTEIN
por: Venkatachalam, M. A., et al.
Publicado: (1970)

Nephrin missense mutations: induction of endoplasmic reticulum stress and cell surface rescue by reduction in chaperone interactions
por: Drozdova, Tetyana, et al.
Publicado: (2013)

Regulation of Autophagy Progress via Lysosomal Depletion by Fluvastatin Nanoparticle Treatment in Breast Cancer Cells
por: Elimam, Hanan, et al.
Publicado: (2020)

STAT1-p53-p21axis-dependent stress-induced progression of chronic nephrosis in adriamycin-induced mouse model
por: Wei, Hua, et al.
Publicado: (2020)

Pharmacological Melanocortin 5 Receptor Activation Attenuates Glomerular Injury and Proteinuria in Rats With Puromycin Aminonucleoside Nephrosis
por: Chen, Bohan, et al.
Publicado: (2022)

Erratum to STAT1-p53-p21axis-dependent stress-induced progression of chronic nephrosis in adriamycin-induced mouse model
Publicado: (2021)

Nephrosis: Its Nature and Incidence in Indians
por: Gupta, S. P.
Publicado: (1935)

The Efficacy of Puromycin and Adriamycin for Induction of Glomerular Failure in Larval Zebrafish Validated by an Assay of Glomerular Permeability Dynamics
por: Rider, Sebastien Andrew, et al.
Publicado: (2018)

Neph1 Is Reduced in Primary Focal Segmental Glomerulosclerosis, Minimal Change Nephrotic Syndrome, and Corresponding Experimental Animal Models of Adriamycin-Induced Nephropathy and Puromycin Aminonucleoside Nephrosis
por: Hulkko, Jenny, et al.
Publicado: (2014)

Acute Renal Failure: Lower Nephron Nephrosis
por: Welt, Louis G., et al.
Publicado: (1951)

Calcium Release at Fertilization in Starfish Eggs Is Mediated by Phospholipase Cγ
por: Carroll, David J., et al.
Publicado: (1997)

Glomerular Endothelial Cell Injury and Damage Precedes That of Podocytes in Adriamycin-Induced Nephropathy
por: Sun, Yu Bo Yang, et al.
Publicado: (2013)

THE ROLE OF ACIDURIA IN THE DEVELOPMENT OF HEMOGLOBINURIC NEPHROSIS IN DEHYDRATED RABBITS
por: Lalich, Joseph J., et al.
Publicado: (1950)

STUDIES ON GLYCOGEN NEPHROSIS IN ALLOXAN-TREATED DIABETIC RATS
por: Curtis, G. W., et al.
Publicado: (1947)

THE NUMBER OF OPEN GLOMERULI IN ACUTE MERCURIC CHLORIDE NEPHROSIS
por: Moore, Robert A., et al.
Publicado: (1931)

A case of mononucleosis infectiosa presenting with cholemic nephrosis
por: Bredewold, Obbo W., et al.
Publicado: (2011)

'Lipoid Nephrosis' Cured after an Attack of Typhoid Fever
por: Gupta, J. C.
Publicado: (1944)

Cholemic Nephrosis: An Autopsy Study of a Forgotten Entity
por: Priyaa, Valli, et al.
Publicado: (2021)

TRANSFER OF AN AUTOIMMUNE NEPHROSIS IN THE RAT BY MEANS OF LYMPH NODE CELLS
por: Hess, Evelyn V., et al.
Publicado: (1962)

THE INFLUENCE OF AVAILABLE FLUID ON THE PRODUCTION OF EXPERIMENTAL HEMOGLOBINURIC NEPHROSIS IN RABBITS
por: Lalich, Joseph J.
Publicado: (1948)

AN ELECTRON MICROSCOPE STUDY OF THE GLOMERULUS IN NEPHROSIS, GLOMERULONEPHRITIS, AND LUPUS ERYTHEMATOSUS
por: Farquhar, Marilyn G., et al.
Publicado: (1957)

Severe hypothyroidism associated with the degree of edema in a patient with nephrosis
por: Kinoshita, Hiroyuki, et al.
Publicado: (2011)

Association of Proteinuria with Urinary Concentration Defect in Puromycin Aminonucleoside Nephrosis
por: Jo, Chor Ho, et al.
Publicado: (2020)

Aspergillus Section Fumigati Pneumonia and Oxalate Nephrosis in a Foal
por: Hattab, Jasmine, et al.
Publicado: (2021)

AMINONUCLEOSIDE NEPHROSIS : I. ELECTRON MICROSCOPIC STUDY OF THE RENAL LESION IN RATS
por: Vernier, Robert L., et al.
Publicado: (1959)

Effects of Celecoxib and Nordihydroguaiaretic Acid on Puromycin Aminonucleoside-Induced Nephrosis in the Rat
por: Lee, Dong Won, et al.
Publicado: (2009)

Effects of Dietary Salt Restriction on Puromycin Aminonucleoside Nephrosis: Preliminary Data
por: Jo, Chor Ho, et al.
Publicado: (2011)

Hydro-Nephrosis. A Short Lecture to the Hospital Assistants of Akola District
por: Hume, T.
Publicado: (1880)

Podocyte Developmental Defects Caused by Adriamycin in Zebrafish Embryos and Larvae: A Novel Model of Glomerular Damage
por: Zennaro, Cristina, et al.
Publicado: (2014)

Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1
por: Zheng, Yongwei, et al.
Publicado: (2015)

Impact of Cyclosporin on Podocyte ZO-1 Expression in Puromycin Aminonucleoside Nephrosis Rats
por: Kim, Beom Seok, et al.
Publicado: (2005)

Trpc6 inactivation confers protection in a model of severe nephrosis in rats
por: Kim, Eun Young, et al.
Publicado: (2018)

Mutations in six nephrosis genes delineate a pathogenic pathway amenable to treatment
por: Ashraf, Shazia, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_nfmgim4g7ecc2kokv92mbj3egg