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ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress

The endoplasmic reticulum (ER) produces about 40% of the nucleated cell’s proteome. ER size and content in molecular chaperones increase upon physiologic and pathologic stresses on activation of unfolded protein responses (UPR). On stress resolution, the mammalian ER is remodeled to pre-stress, phys...

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Detalles Bibliográficos
Autores principales: Loi, Marisa, Raimondi, Andrea, Morone, Diego, Molinari, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838186/
https://www.ncbi.nlm.nih.gov/pubmed/31699981
http://dx.doi.org/10.1038/s41467-019-12991-z