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Direct observation of Thermomyces lanuginosus lipase diffusional states by Single Particle Tracking and their remodeling by mutations and inhibition

Lipases are interfacially activated enzymes that catalyze the hydrolysis of ester bonds and constitute prime candidates for industrial and biotechnological applications ranging from detergent industry, to chiral organic synthesis. As a result, there is an incentive to understand the mechanisms under...

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Detalles Bibliográficos
Autores principales: Bohr, Søren S.-R., Lund, Philip M., Kallenbach, Amalie S., Pinholt, Henrik, Thomsen, Johannes, Iversen, Lars, Svendsen, Allan, Christensen, Sune M., Hatzakis, Nikos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838188/
https://www.ncbi.nlm.nih.gov/pubmed/31700110
http://dx.doi.org/10.1038/s41598-019-52539-1