Computational and NMR studies of RNA duplexes with an internal pseudouridine-adenosine base pair

Pseudouridine (Ψ) is the most common chemical modification present in RNA. In general, Ψ increases the thermodynamic stability of RNA. However, the degree of stabilization depends on the sequence and structural context. To explain experimentally observed sequence dependence of the effect of Ψ on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Deb, Indrajit, Popenda, Łukasz, Sarzyńska, Joanna, Małgowska, Magdalena, Lahiri, Ansuman, Gdaniec, Zofia, Kierzek, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838189/
https://www.ncbi.nlm.nih.gov/pubmed/31700156
http://dx.doi.org/10.1038/s41598-019-52637-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838189/
https://www.ncbi.nlm.nih.gov/pubmed/31700156
http://dx.doi.org/10.1038/s41598-019-52637-0

Ejemplares similares