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Computational and NMR studies of RNA duplexes with an internal pseudouridine-adenosine base pair

Pseudouridine (Ψ) is the most common chemical modification present in RNA. In general, Ψ increases the thermodynamic stability of RNA. However, the degree of stabilization depends on the sequence and structural context. To explain experimentally observed sequence dependence of the effect of Ψ on the...

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Detalles Bibliográficos
Autores principales:	Deb, Indrajit, Popenda, Łukasz, Sarzyńska, Joanna, Małgowska, Magdalena, Lahiri, Ansuman, Gdaniec, Zofia, Kierzek, Ryszard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838189/ https://www.ncbi.nlm.nih.gov/pubmed/31700156 http://dx.doi.org/10.1038/s41598-019-52637-0

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