Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP

The mammalian Staufen proteins (Stau1 and Stau2) mediate degradation of mRNA containing complex secondary structures in their 3’-untranslated region (UTR) through a pathway known as Staufen-mediated mRNA decay (SMD). This pathway also involves the RNA helicase UPF1, which is best known for its role...

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Detalles Bibliográficos
Autores principales: Gowravaram, Manjeera, Schwarz, Juliane, Khilji, Sana K., Urlaub, Henning, Chakrabarti, Sutapa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838198/
https://www.ncbi.nlm.nih.gov/pubmed/31699982
http://dx.doi.org/10.1038/s41467-019-13080-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838198/
https://www.ncbi.nlm.nih.gov/pubmed/31699982
http://dx.doi.org/10.1038/s41467-019-13080-x

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