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Insights into the assembly and architecture of a Staufen-mediated mRNA decay (SMD)-competent mRNP
The mammalian Staufen proteins (Stau1 and Stau2) mediate degradation of mRNA containing complex secondary structures in their 3’-untranslated region (UTR) through a pathway known as Staufen-mediated mRNA decay (SMD). This pathway also involves the RNA helicase UPF1, which is best known for its role...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838198/ https://www.ncbi.nlm.nih.gov/pubmed/31699982 http://dx.doi.org/10.1038/s41467-019-13080-x |