Differential Inhibition of Human and Trypanosome Ubiquitin E1S by TAK-243 Offers Possibilities for Parasite Selective Inhibitors

Novel strategies to target Trypanosoma brucei, Trypanosoma cruzi and Leishmania are urgently needed to generate better and safer drugs against Human African Trypanosomiasis, Chagas disease and Leishmaniasis, respectively. Here, we investigated the feasibility of selectively targeting in trypanosomat...

Descripción completa

Detalles Bibliográficos
Autores principales: Boer, D. Roeland, Bijlmakers, Marie-José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838199/
https://www.ncbi.nlm.nih.gov/pubmed/31700050
http://dx.doi.org/10.1038/s41598-019-52618-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838199/
https://www.ncbi.nlm.nih.gov/pubmed/31700050
http://dx.doi.org/10.1038/s41598-019-52618-3

Ejemplares similares