Recombinant B2L and Kisspeptin-54 DNA Vaccine Induces Immunity Against Orf Virus and Inhibits Spermatogenesis In Rats

Orf is a highly contagious zoonotic disease of small ruminants caused by Parapoxvirus. Kisspeptin, encoded by the KISS1 gene with its cognate receptor GPR-54 is recognized as an upstream orchestrator in the hypothalamic-pituitary-gonadal axis. This study was designed to construct a DNA vaccine that...

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Detalles Bibliográficos
Autores principales: Wassie, Teketay, Fanmei, Zeng, Jiang, Xunping, Liu, Guiqiong, Girmay, Shishay, Min, Zhang, Chenhui, Liu, Bo, Dong Dong, Ahmed, Sohail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838309/
https://www.ncbi.nlm.nih.gov/pubmed/31700161
http://dx.doi.org/10.1038/s41598-019-52744-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838309/
https://www.ncbi.nlm.nih.gov/pubmed/31700161
http://dx.doi.org/10.1038/s41598-019-52744-y

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