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LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells

Ferroptosis is a non-apoptotic, iron-dependent oxidative form of cell death that is specifically induced by erastin in RAS mutant cancer cells. Ferroptotic cell death is the result of membrane lipid peroxide damage caused by the accumulation of hydroxyl radicals derived from H(2)O(2) by the Fenton r...

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Detalles Bibliográficos
Autores principales: Qi, Wenchuan, Li, Zhenhua, Xia, Longjiang, Dai, Jiangshan, Zhang, Qiao, Wu, Chuanfang, Xu, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838315/
https://www.ncbi.nlm.nih.gov/pubmed/31700067
http://dx.doi.org/10.1038/s41598-019-52837-8