Discovery of Novel Multi-target Inhibitor of angiotensin type 1 receptor and neprilysin inhibitors from Traditional Chinese Medicine

Angiotensin II type-1 receptor–neprilysin inhibitor (ARNi) is consisted of Angiotensin II type-1 receptor (AT1) antagonist and neprilysin (NEP) inhibitor, which could simultaneously increase the vasodilators of the natriuretic peptides and antagonize vasoconstrictors of Ang II. ARNi has been proved...

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Detalles Bibliográficos
Autores principales: Huo, Xiaoqian, Qiao, Liansheng, Chen, Yankun, Chen, Xi, He, Yusu, Zhang, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838339/
https://www.ncbi.nlm.nih.gov/pubmed/31700033
http://dx.doi.org/10.1038/s41598-019-52309-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838339/
https://www.ncbi.nlm.nih.gov/pubmed/31700033
http://dx.doi.org/10.1038/s41598-019-52309-z

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