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Tracking the polyclonal neutralizing antibody response to a dengue virus serotype 1 type-specific epitope across two populations in Asia and the Americas

The four dengue virus serotypes (DENV1-4) cause major public health problems worldwide. Highly neutralizing type-specific human monoclonal antibodies (hmAbs) target conformation-dependent epitopes on the DENV envelope protein, including 1F4, a DENV1 type-specific hmAb. Using a recombinant DENV2 viru...

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Detalles Bibliográficos
Autores principales: Andrade, Daniela V., Warnes, Colin, Young, Ellen, Katzelnick, Leah C., Balmaseda, Angel, de Silva, Aravinda M., Baric, Ralph S., Harris, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838341/
https://www.ncbi.nlm.nih.gov/pubmed/31700029
http://dx.doi.org/10.1038/s41598-019-52511-z