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A single faecal microbiota transplantation modulates the microbiome and improves clinical manifestations in a rat model of colitis

BACKGROUND: Faecal microbiota transplantation (FMT) is a novel potential therapy for inflammatory bowel diseases, but it is poorly characterised. METHODS: We evaluated the performance of the mouse and rat as a pre-clinical model for human microbiota engraftment. We then characterised the effect of a...

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Detalles Bibliográficos
Autores principales: Lleal, Marina, Sarrabayrouse, Guillaume, Willamil, Joseane, Santiago, Alba, Pozuelo, Marta, Manichanh, Chaysavanh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838378/
https://www.ncbi.nlm.nih.gov/pubmed/31628021
http://dx.doi.org/10.1016/j.ebiom.2019.10.002