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Metabolomic profiling identifies pathways associated with minimal residual disease in childhood acute lymphoblastic leukaemia

BACKGROUND: End-induction minimal residual disease (MRD) is the strongest predictor of relapse in paediatric acute lymphoblastic leukaemia (ALL), but an understanding of the biological pathways underlying early treatment response remains elusive. We hypothesized that metabolomic profiling of diagnos...

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Detalles Bibliográficos
Autores principales: Schraw, Jeremy M., Junco, Jacob J., Brown, Austin L., Scheurer, Michael E., Rabin, Karen R., Lupo, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838385/
https://www.ncbi.nlm.nih.gov/pubmed/31631039
http://dx.doi.org/10.1016/j.ebiom.2019.09.033