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Accumulation of mitochondrial 7S DNA in idiopathic and LRRK2 associated Parkinson's disease
BACKGROUND: Both idiopathic and familial Parkinson's disease are associated with mitochondrial dysfunction. Mitochondria have their own mitochondrial DNA (mtDNA) and previous studies have reported that the release of mtDNA is a biomarker of Parkinson's disease. METHODS: We have now investi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838390/ https://www.ncbi.nlm.nih.gov/pubmed/31631040 http://dx.doi.org/10.1016/j.ebiom.2019.09.015 |