Degradation of GRK2 and AKT is an early and detrimental event in myocardial ischemia/reperfusion

BACKGROUND: Identification of signaling pathways altered at early stages after cardiac ischemia/reperfusion (I/R) is crucial to develop timely therapies aimed at reducing I/R injury. The expression of G protein-coupled receptor kinase 2 (GRK2), a key signaling hub, is up-regulated in the long-term i...

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Detalles Bibliográficos
Autores principales: Penela, Petronila, Inserte, Javier, Ramos, Paula, Rodriguez-Sinovas, Antonio, Garcia-Dorado, David, Mayor, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838402/
https://www.ncbi.nlm.nih.gov/pubmed/31594751
http://dx.doi.org/10.1016/j.ebiom.2019.09.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838402/
https://www.ncbi.nlm.nih.gov/pubmed/31594751
http://dx.doi.org/10.1016/j.ebiom.2019.09.019

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