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HBV-encoded miR-2 functions as an oncogene by downregulating TRIM35 but upregulating RAN in liver cancer cells

BACKGROUND: Hepatitis B virus (HBV) infection has been well established as a high-risk factor for the carcinogenesis of hepatocellular carcinoma (HCC). Cellular microRNA (miRNA) is involved in tumorigenesis by accelerating the malignant phenotype in HCC. However, whether HBV can encode miRNAs that c...

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Detalles Bibliográficos
Autores principales: Yao, Lili, Zhou, Yadi, Sui, Zhenhua, Zhang, Yanling, Liu, Yankun, Xie, Hong, Gao, Huijie, Fan, Hongxia, Zhang, Yi, Liu, Min, Li, Shengping, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838411/
https://www.ncbi.nlm.nih.gov/pubmed/31530503
http://dx.doi.org/10.1016/j.ebiom.2019.09.012