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Increased proton-sensing receptor GPR4 signalling promotes colorectal cancer progression by activating the hippo pathway

BACKGROUND: Colorectal cancer (CRC) is one of the high incidences tumours and is ranked second in cancer-related mortality. Even though great progress has been made, there are no effective therapeutic strategies for late stage and metastatic CRC patients. Acidity is one characteristic of the tumour...

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Detalles Bibliográficos
Autores principales: Yu, Minhao, Cui, Ran, Huang, Yizhou, Luo, Yang, Qin, Shaolan, Zhong, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838423/
https://www.ncbi.nlm.nih.gov/pubmed/31530502
http://dx.doi.org/10.1016/j.ebiom.2019.09.016