Cargando…

USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway

BACKGROUND: USP11 is an ubiquitin-specific protease that plays an important role in tumor progression via different mechanisms. However, the expression and prognostic significance of USP11 in colorectal cancer (CRC) remain unknown. METHODS: Bioinformatics analyses, qRT-PCR, western blotting, and imm...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Hongze, Ou, Baochi, Zhao, Senlin, Liu, Xueni, Song, Liwei, Liu, Xisheng, Wang, Rangrang, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838424/
https://www.ncbi.nlm.nih.gov/pubmed/31521612
http://dx.doi.org/10.1016/j.ebiom.2019.08.061