Cargando…

USP11 promotes growth and metastasis of colorectal cancer via PPP1CA-mediated activation of ERK/MAPK signaling pathway

BACKGROUND: USP11 is an ubiquitin-specific protease that plays an important role in tumor progression via different mechanisms. However, the expression and prognostic significance of USP11 in colorectal cancer (CRC) remain unknown. METHODS: Bioinformatics analyses, qRT-PCR, western blotting, and imm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Hongze, Ou, Baochi, Zhao, Senlin, Liu, Xueni, Song, Liwei, Liu, Xisheng, Wang, Rangrang, Peng, Zhihai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Research paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838424/ https://www.ncbi.nlm.nih.gov/pubmed/31521612 http://dx.doi.org/10.1016/j.ebiom.2019.08.061

Ejemplares similares

USP11 induce resistance to 5-Fluorouracil in Colorectal Cancer through activating autophagy by stabilizing VCP
por: Sun, Hongze, et al.
Publicado: (2021)

Polo-like kinase 3 inhibits glucose metabolism in colorectal cancer by targeting HSP90/STAT3/HK2 signaling
por: Ou, Baochi, et al.
Publicado: (2019)

Impaired AGO2/miR-185-3p/NRP1 axis promotes colorectal cancer metastasis
por: Liu, Xisheng, et al.
Publicado: (2021)

Keratin 80 promotes migration and invasion of colorectal carcinoma by interacting with PRKDC via activating the AKT pathway
por: Li, Changcan, et al.
Publicado: (2018)

Panx1 promotes invasion-metastasis cascade in hepatocellular carcinoma
por: Shi, Guangjun, et al.
Publicado: (2019)

Global burden of primary liver cancer by five etiologies and global prediction by 2035 based on global burden of disease study 2019
por: Liu, Yuan, et al.
Publicado: (2022)

Comprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer
por: Xie, Wenjun, et al.
Publicado: (2021)

Tumor-derived CXCL5 promotes human colorectal cancer metastasis through activation of the ERK/Elk-1/Snail and AKT/GSK3β/β-catenin pathways
por: Zhao, Jingkun, et al.
Publicado: (2017)

ERK-mediated Cytoplasmic Retention of USP11 Contributes to Breast Cancer Cell Proliferation by Stabilizing Cytoplasmic p21
por: Li, Ling, et al.
Publicado: (2022)

CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer
por: Ou, Baochi, et al.
Publicado: (2016)

Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11
por: Vlasschaert, Caitlyn, et al.
Publicado: (2015)

Correction: CCR4 promotes metastasis via ERK/NF-κB/MMP13 pathway and acts downstream of TNF-α in colorectal cancer
por: Ou, Baochi, et al.
Publicado: (2017)

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK
por: Cho, Eunice, et al.
Publicado: (2021)

Potential Role and Clinical Value of PPP2CA in Hepatocellular Carcinoma
por: Yang, Cheng-Lei, et al.
Publicado: (2021)

KIF18A interacts with PPP1CA to promote the malignant development of glioblastoma
por: Yang, Ji, et al.
Publicado: (2023)

MAPK-ERK Pathway
por: Park, Jong-In
Publicado: (2023)

PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway
por: Tang, Bo, et al.
Publicado: (2019)

USP11 role in colorectal cancer growing and metastatisation
por: Malapelle, Umberto
Publicado: (2019)

TRIM67 inhibits tumor proliferation and metastasis by mediating MAPK11 in Colorectal Cancer
por: Liu, Ying, et al.
Publicado: (2020)

Dietary potassium stimulates Ppp1Ca-Ppp1r1a dephosphorylation of kidney NaCl cotransporter and reduces blood pressure
por: Grimm, P. Richard, et al.
Publicado: (2023)

ERK/MAPK signalling pathway and tumorigenesis
por: Guo, Yan-Jun, et al.
Publicado: (2020)

Restoration of PPP2CA expression reverses epithelial-to-mesenchymal transition and suppresses prostate tumour growth and metastasis in an orthotopic mouse model
por: Bhardwaj, A, et al.
Publicado: (2014)

Genetic variants in PPP2CA are associated with gastric cancer risk in a Chinese population
por: Huang, Tongtong, et al.
Publicado: (2017)

[Retracted] PEA15 promotes liver metastasis of colorectal cancer by upregulating the ERK/MAPK signaling pathway
por: Tang, Bo, et al.
Publicado: (2023)

The Dual Role of USP11 in Cancer
por: Guo, Tuanjie, et al.
Publicado: (2022)

CMaf-Inducing Protein Promotes LUAD Proliferation and Metastasis by Activating the MAPK/ERK Pathway
por: Yu, Xiao-Yan, et al.
Publicado: (2022)

Conditional Knockout in Mice Reveals the Critical Roles of Ppp2ca in Epidermis Development
por: Fang, Chao, et al.
Publicado: (2016)

The Downregulation of eIF3a Contributes to Vemurafenib Resistance in Melanoma by Activating ERK via PPP2R1B
por: Jiang, Shi-Long, et al.
Publicado: (2021)

Systemic Sympathoexcitation Was Associated with Paraventricular Hypothalamic Phosphorylation of Synaptic CaMKIIα and MAPK/ErK
por: Ogundele, Olalekan M., et al.
Publicado: (2017)

Genome-Wide Association Study of Tacrolimus Pharmacokinetics Identifies Novel Single Nucleotide Polymorphisms in the Convalescence and Stabilization Periods of Post-transplant Liver Function
por: Liu, Yuan, et al.
Publicado: (2019)

Estradiol is significantly associated with prognosis in non-surgical liver cancer patients: from bench to bedside
por: Wang, Rangrang, et al.
Publicado: (2021)

Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into β-arrestin-dependent ERK signaling
por: Liu, Hongda, et al.
Publicado: (2016)

Quantum-based modeling implies that bidentate Arg(89)-substrate binding enhances serine/threonine protein phosphatase-2A(PPP2R5D/PPP2R1A/PPP2CA)-mediated dephosphorylation
por: Salter, E. Alan, et al.
Publicado: (2023)

PPP5C promotes cell proliferation and survival in human prostate cancer by regulating of the JNK and ERK1/2 phosphorylation
por: Lv, Jian-Min, et al.
Publicado: (2018)

Improving GNSS PPP Convergence: The Case of Atmospheric-Constrained, Multi-GNSS PPP-AR
por: Aggrey, John, et al.
Publicado: (2019)

miR-4775 promotes colorectal cancer invasion and metastasis via the Smad7/TGFβ-mediated epithelial to mesenchymal transition
por: Zhao, Senlin, et al.
Publicado: (2017)

CAMTA1–PPP3CA–NFATc4 multi-protein complex mediates the resistance of colorectal cancer to oxaliplatin
por: Pan, Ruijun, et al.
Publicado: (2022)

MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4
por: Cheng, Dantong, et al.
Publicado: (2016)

Glutamine up-regulates MAPK phosphatase-1 induction via activation of Ca(2+)→ ERK cascade pathway
por: Ayush, Otgonzaya, et al.
Publicado: (2016)

PS: 10$^{13}$ ppp
Publicado: (1975)

Cannot write session to /tmp/vufind_sessions/sess_juk077uem14ek0j4ro0738862l