Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites

Although the robust antidepressant effects of the N-methyl-d-aspartate receptor (NMDAR) antagonist ketamine in patients with treatment-resistant depression are beyond doubt, the precise molecular and cellular mechanisms underlying its antidepressant effects remain unknown. NMDAR inhibition and the s...

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Detalles Bibliográficos
Autores principales: Yang, Chun, Yang, Jianjun, Luo, Ailin, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838457/
https://www.ncbi.nlm.nih.gov/pubmed/31699965
http://dx.doi.org/10.1038/s41398-019-0624-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838457/
https://www.ncbi.nlm.nih.gov/pubmed/31699965
http://dx.doi.org/10.1038/s41398-019-0624-1

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