Contextualized genome-scale model unveils high-order metabolic effects of the specific growth rate and oxygenation level in recombinant Pichia pastoris

Pichia pastoris is recognized as a biotechnological workhorse for recombinant protein expression. The metabolic performance of this microorganism depends on genetic makeup and culture conditions, amongst which the specific growth rate and oxygenation level are critical. Despite their importance, onl...

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Detalles Bibliográficos
Autores principales: Torres, Paulina, Saa, Pedro A., Albiol, Joan, Ferrer, Pau, Agosin, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838487/
https://www.ncbi.nlm.nih.gov/pubmed/31720218
http://dx.doi.org/10.1016/j.mec.2019.e00103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838487/
https://www.ncbi.nlm.nih.gov/pubmed/31720218
http://dx.doi.org/10.1016/j.mec.2019.e00103

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