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Application of 2′-OMethylRNA′ Antisense Oligomer to Control Candida albicans EFG1 Virulence Determinant

Antisense oligomers and their analogs have been successfully utilized to silence gene expression for the treatment of many human diseases; however, the control of yeast’s virulence determinants has never been exploited before. In this sense, this work is based on the key hypothesis that if a pathoge...

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Detalles Bibliográficos
Autores principales: Araújo, Daniela, Azevedo, Nuno Miguel, Barbosa, Ana, Almeida, Carina, Rodrigues, Maria Elisa, Henriques, Mariana, Silva, Sónia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838528/
https://www.ncbi.nlm.nih.gov/pubmed/31671344
http://dx.doi.org/10.1016/j.omtn.2019.09.016