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Application of 2′-OMethylRNA′ Antisense Oligomer to Control Candida albicans EFG1 Virulence Determinant
Antisense oligomers and their analogs have been successfully utilized to silence gene expression for the treatment of many human diseases; however, the control of yeast’s virulence determinants has never been exploited before. In this sense, this work is based on the key hypothesis that if a pathoge...
Autores principales: | Araújo, Daniela, Azevedo, Nuno Miguel, Barbosa, Ana, Almeida, Carina, Rodrigues, Maria Elisa, Henriques, Mariana, Silva, Sónia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838528/ https://www.ncbi.nlm.nih.gov/pubmed/31671344 http://dx.doi.org/10.1016/j.omtn.2019.09.016 |
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