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Target-Triggered Polymerization of Branched DNA Enables Enzyme-free and Fast Discrimination of Single-Base Changes

Single-base changes lead to important biological and biomedical implications; however, the discrimination of single-base changes from normal DNA always remains a grand challenge. Herein we developed a DNA recognition and amplification system based on artificial branched DNA, namely, target-triggered...

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Detalles Bibliográficos
Autores principales: Dong, Yuhang, Yao, Chi, Wang, Zhi, Luo, Dan, Yang, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838547/
https://www.ncbi.nlm.nih.gov/pubmed/31675552
http://dx.doi.org/10.1016/j.isci.2019.10.029