Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis

The discovery that prion protein can misfold into a pathological conformation that encodes structural information capable of both propagation and inducing severe neuropathology has revolutionized our understanding of neurodegenerative disease. Many neurodegenerative diseases with a protein misfoldin...

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Detalles Bibliográficos
Autores principales: McAlary, Luke, Plotkin, Steven S., Yerbury, Justin J., Cashman, Neil R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838634/
https://www.ncbi.nlm.nih.gov/pubmed/31736708
http://dx.doi.org/10.3389/fnmol.2019.00262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838634/
https://www.ncbi.nlm.nih.gov/pubmed/31736708
http://dx.doi.org/10.3389/fnmol.2019.00262

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