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Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis
The discovery that prion protein can misfold into a pathological conformation that encodes structural information capable of both propagation and inducing severe neuropathology has revolutionized our understanding of neurodegenerative disease. Many neurodegenerative diseases with a protein misfoldin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838634/ https://www.ncbi.nlm.nih.gov/pubmed/31736708 http://dx.doi.org/10.3389/fnmol.2019.00262 |