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Chondral Differentiation of Induced Pluripotent Stem Cells Without Progression Into the Endochondral Pathway
A major problem with chondrocytes derived in vitro from stem cells is undesired hypertrophic degeneration, to which articular chondrocytes (ACs) are resistant. As progenitors of all adult tissues, induced pluripotent stem cells (iPSCs) are in theory able to form stable articular cartilage. In vitro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838640/ https://www.ncbi.nlm.nih.gov/pubmed/31737632 http://dx.doi.org/10.3389/fcell.2019.00270 |