Cargando…

Chondral Differentiation of Induced Pluripotent Stem Cells Without Progression Into the Endochondral Pathway

A major problem with chondrocytes derived in vitro from stem cells is undesired hypertrophic degeneration, to which articular chondrocytes (ACs) are resistant. As progenitors of all adult tissues, induced pluripotent stem cells (iPSCs) are in theory able to form stable articular cartilage. In vitro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diederichs, Solvig, Klampfleuthner, Felicia A. M., Moradi, Babak, Richter, Wiltrud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838640/ https://www.ncbi.nlm.nih.gov/pubmed/31737632 http://dx.doi.org/10.3389/fcell.2019.00270

Ejemplares similares

Significance of MEF2C and RUNX3 Regulation for Endochondral Differentiation of Human Mesenchymal Progenitor Cells
por: Dreher, Simon I., et al.
Publicado: (2020)

Initial WNT/β-Catenin Activation Enhanced Mesoderm Commitment, Extracellular Matrix Expression, Cell Aggregation and Cartilage Tissue Yield From Induced Pluripotent Stem Cells
por: Kreuser, Ursula, et al.
Publicado: (2020)

Stage-Dependent Activity and Pro-Chondrogenic Function of PI3K/AKT during Cartilage Neogenesis from Mesenchymal Stromal Cells
por: Klampfleuthner, Felicia A. M., et al.
Publicado: (2022)

Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation
por: Dexheimer, Verena, et al.
Publicado: (2016)

Current progress on in vitro differentiation of ovarian follicles from pluripotent stem cells
por: Wu, Genie Min Ju, et al.
Publicado: (2023)

Differentiation of human induced pluripotent stem cells into cortical neural stem cells
por: Neaverson, Alexandra, et al.
Publicado: (2023)

MiR-181a Targets RSPO2 and Regulates Bone Morphogenetic Protein – WNT Signaling Crosstalk During Chondrogenic Differentiation of Mesenchymal Stromal Cells
por: Melnik, Svitlana, et al.
Publicado: (2021)

Induced pluripotent stem cells: Generation methods and a new perspective in COVID-19 research
por: Karami, Zahra, et al.
Publicado: (2023)

Rapid and Reproducible Differentiation of Hematopoietic and T Cell Progenitors From Pluripotent Stem Cells
por: Flippe, Léa, et al.
Publicado: (2020)

Differentiation of pluripotent stem cells for modeling human skin development and potential applications
por: Oceguera-Yanez, Fabian, et al.
Publicado: (2022)

Mature Myotubes Generated From Human-Induced Pluripotent Stem Cells Without Forced Gene Expression
por: Fujiwara, Kei, et al.
Publicado: (2022)

Characterization of DNA Methylomic Signatures in Induced Pluripotent Stem Cells During Neuronal Differentiation
por: Imm, Jennifer, et al.
Publicado: (2021)

Zinc Maintains Embryonic Stem Cell Pluripotency and Multilineage Differentiation Potential via AKT Activation
por: Mnatsakanyan, Hayk, et al.
Publicado: (2019)

Tenogenic Induction From Induced Pluripotent Stem Cells Unveils the Trajectory Towards Tenocyte Differentiation
por: Yoshimoto, Yuki, et al.
Publicado: (2022)

Modeling Klinefelter Syndrome Using Induced Pluripotent Stem Cells Reveals Impaired Germ Cell Differentiation
por: Botman, Olivier, et al.
Publicado: (2020)

Energy Metabolism Regulates Stem Cell Pluripotency
por: Tsogtbaatar, Enkhtuul, et al.
Publicado: (2020)

Editorial: Reviews in induced pluripotent stem cells
por: Dottori, Mirella, et al.
Publicado: (2023)

Selective Retinoic Acid Receptor γ Antagonist 7C is a Potent Enhancer of BMP-Induced Ectopic Endochondral Bone Formation
por: Tateiwa, Daisuke, et al.
Publicado: (2022)

Look who’s TORking: mTOR-mediated integration of cell status and external signals during limb development and endochondral bone growth
por: H’ng, Chee Ho, et al.
Publicado: (2023)

Mammalian SWI/SNF Chromatin Remodeling Complexes in Embryonic Stem Cells: Regulating the Balance Between Pluripotency and Differentiation
por: Ye, Ying, et al.
Publicado: (2021)

Differentiation and Application of Human Pluripotent Stem Cells Derived Cardiovascular Cells for Treatment of Heart Diseases: Promises and Challenges
por: Gao, Yu, et al.
Publicado: (2021)

Culture of Murine Embryonic Metatarsals: A Physiological Model of Endochondral Ossification
por: Houston, Dean A., et al.
Publicado: (2016)

Emerging Methods for Enhancing Pluripotent Stem Cell Expansion
por: Chan, Sarah W., et al.
Publicado: (2020)

Simulated Microgravity Potentiates Hematopoietic Differentiation of Human Pluripotent Stem Cells and Supports Formation of 3D Hematopoietic Cluster
por: Ma, Chiyuan, et al.
Publicado: (2022)

Using Advanced Cell Culture Techniques to Differentiate Pluripotent Stem Cells and Recreate Tissue Structures Representative of Teratoma Xenografts
por: Smith, L. A., et al.
Publicado: (2021)

Methylation and Expression of Mutant FUS in Motor Neurons Differentiated From Induced Pluripotent Stem Cells From ALS Patients
por: Hartung, T., et al.
Publicado: (2021)

Exogenous LIN28 Is Required for the Maintenance of Self-Renewal and Pluripotency in Presumptive Porcine-Induced Pluripotent Stem Cells
por: Chakritbudsabong, Warunya, et al.
Publicado: (2021)

Generation of Vestibular Tissue-Like Organoids From Human Pluripotent Stem Cells Using the Rotary Cell Culture System
por: Mattei, Cristiana, et al.
Publicado: (2019)

Induced Pluripotent Stem Cells for Traumatic Spinal Cord Injury
por: Khazaei, Mohamad, et al.
Publicado: (2017)

Utilization of Human Induced Pluripotent Stem Cells for Cardiac Repair
por: Fan, Chengming, et al.
Publicado: (2020)

Ventral Telencephalic Patterning Protocols for Induced Pluripotent Stem Cells
por: Krajka, Victor, et al.
Publicado: (2021)

Research Advances in Gametogenesis and Embryogenesis Using Pluripotent Stem Cells
por: Luo, Yuxin, et al.
Publicado: (2022)

Uncovering Inherited Cardiomyopathy With Human Induced Pluripotent Stem Cells
por: Jiang, Xue, et al.
Publicado: (2021)

Editorial: Methods and advances in induced pluripotent stem cells—ophthalmology
por: Armstrong, Lyle, et al.
Publicado: (2023)

Neural Stem Cells and Methods for Their Generation From Induced Pluripotent Stem Cells in vitro
por: Galiakberova, Adelya A., et al.
Publicado: (2020)

miR-212/132-Enriched Extracellular Vesicles Promote Differentiation of Induced Pluripotent Stem Cells Into Pancreatic Beta Cells
por: Bai, Chunyu, et al.
Publicado: (2021)

An Isogenic Collection of Pluripotent Stem Cell Lines With Elevated α-Synuclein Expression Validated for Neural Induction and Cortical Neuron Differentiation
por: Natalwala, Ammar, et al.
Publicado: (2022)

A new mouse model of post-traumatic joint injury allows to identify the contribution of Gli1+ mesenchymal progenitors in arthrofibrosis and acquired heterotopic endochondral ossification
por: Magallanes, Jenny, et al.
Publicado: (2022)

Murine pluripotent stem cells that escape differentiation inside teratomas maintain pluripotency
por: Pei, Yangli, et al.
Publicado: (2018)

Menaquinone-7 Supplementation Improves Osteogenesis in Pluripotent Stem Cell Derived Mesenchymal Stem Cells
por: Akbulut, Asim Cengiz, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_brhcdh5302on0k6d88gidr20am