High-Throughput Assessment of Kinome-wide Activation States

Aberrant kinase activity has been linked to a variety of disorders; however, methods to probe kinase activation states in cells have been lacking. Until now, kinase activity has mainly been deduced from either protein expression or substrate phosphorylation levels. Here, we describe a strategy to di...

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Detalles Bibliográficos
Autores principales: Schmidlin, Thierry, Debets, Donna O., van Gelder, Charlotte A.G.H., Stecker, Kelly E., Rontogianni, Stamatia, van den Eshof, Bart L., Kemper, Kristel, Lips, Esther H., van den Biggelaar, Maartje, Peeper, Daniel S., Heck, Albert J.R., Altelaar, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838672/
https://www.ncbi.nlm.nih.gov/pubmed/31521607
http://dx.doi.org/10.1016/j.cels.2019.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838672/
https://www.ncbi.nlm.nih.gov/pubmed/31521607
http://dx.doi.org/10.1016/j.cels.2019.08.005

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