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Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation
Enhancers can regulate the promoters of their target genes over very large genomic distances. It is widely assumed that mechanisms of enhancer action involve the reorganization of three-dimensional chromatin architecture, but this is poorly understood. The predominant model involves physical enhance...
Autores principales: | Benabdallah, Nezha S., Williamson, Iain, Illingworth, Robert S., Kane, Lauren, Boyle, Shelagh, Sengupta, Dipta, Grimes, Graeme R., Therizols, Pierre, Bickmore, Wendy A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838673/ https://www.ncbi.nlm.nih.gov/pubmed/31494034 http://dx.doi.org/10.1016/j.molcel.2019.07.038 |
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