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Proteoglycan degradation mimics static compression by altering the natural gradients in fibrillar organisation in cartilage

Structural and associated biomechanical gradients within biological tissues are important for tissue functionality and preventing damaging interfacial stress concentrations. Articular cartilage possesses an inhomogeneous structure throughout its thickness, driving the associated variation in the bio...

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Detalles Bibliográficos
Autores principales: Inamdar, Sheetal R., Barbieri, Ettore, Terrill, Nicholas J., Knight, Martin M., Gupta, Himadri S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838783/
https://www.ncbi.nlm.nih.gov/pubmed/31374336
http://dx.doi.org/10.1016/j.actbio.2019.07.055