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Stimulation of cell invasion by the Golgi Ion Channel GAAP/TMBIM4 via an H(2)O(2)-Dependent Mechanism

The mechanisms by which the Golgi apparatus (GA) impacts on cell invasion are poorly understood. The human Golgi Anti-Apoptotic Protein (hGAAP, also known as TMBIM4) is a highly conserved Golgi cation channel that modulates intracellular Ca(2+) fluxes. Human GAAP is expressed in all human tissues, i...

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Detalles Bibliográficos
Autores principales: Almeida, Nuno, Carrara, Guia, Palmeira, Carlos M., Fernandes, Ana S., Parsons, Maddy, Smith, Geoffrey L., Saraiva, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838802/
https://www.ncbi.nlm.nih.gov/pubmed/31693977
http://dx.doi.org/10.1016/j.redox.2019.101361